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    • 专利摘要:
    Device (1) for collecting blood or a blood compound, comprising a tube (10), a piston assembly (50), a handle assembly (30) clipable to the piston assembly (50), and a pierceable sealing element (70) ) which prevents the passage of fluid from a sealed inner space (15a) of the tube (10) to a longitudinal interior cavity (35) of the handle assembly (30) located adjacent to a separable area (33) of the handle assembly (30). In use, the handle assembly (30) is pushed to the bottom of the tube (10), causing the clipping of the handle assembly (30) to the piston assembly (50); then the handle assembly (30) and the piston assembly (50) are drawn back, forming a vacuum in the space (15a); the piston assembly (50) is clipped to an end cap (90) of the tube (10) and the grip portion (32) of the handle assembly (30) is separated, obtaining a vacuum container with a pierceable closure. (Machine-translation by Google Translate, not legally binding)
    公开号:ES2593042A1
    申请号:ES201530776
    申请日:2015-06-03
    公开日:2016-12-05
    发明作者:Eduardo Anitua Aldecoa
    申请人:BTI Biotechnology Insttitute；
    IPC主号:
    专利说明:

    BLOOD COLLECTION OR BLOOD COMPOUND DEVICEDESCRIPTION
     5 Technical sector

    The invention relates to a device for collecting blood or a blood compound as a result of suction or vacuum, and in particular a device having a tube, a piston and a detachable handle 10 for generating the vacuum in the tube moments before If the device is used, guaranteeing optimum vacuum conditions when the device is used, for example, to collect blood taken from a patient.
     fifteen State of the art

    For the extraction of blood from the human or animal body, sealed and vacuum closed tubes are generally used, that is, with a pressure of the inner atmosphere less than the pressure at which blood is found in the veins. Generally, the tubes are closed by a plug or pierceable closure, such as a septum. The blood is extracted by inserting a hypodermic needle into the vein or artery of the person or animal, said needle being connected to an opposite needle, which in turn pierces the pierceable closure of the tube and is inserted into the interior of the vacuum closed tube. When the vein or artery is communicated with the inside of the tube, a blood draw occurs due to pressure differences from the vein or artery to the tube, which ends when the needle is removed from the body.
     30
    The vacuum tubes used to draw blood have a simple configuration, in the form of an elongated receptacle closed at one end by said perforable closure, and which is provided with vacuum at the factory, that is, during its manufacture. Normally, health centers or agencies are supplied with a large number of tubes 35 that are stored and used only when it is
    necessary. Unfortunately, the capacity of the receptacles and perforable closures to maintain the vacuum created at the factory is limited, since the tubes lose their optimum vacuum conditions over time through the joints between parts and even through the walls of the tube. To avoid loss of vacuum, the tubes can be manufactured with greater thicknesses and / or with components that provide a more tight seal, which results in an increase in the manufacturing cost of the tubes. It is also possible to stop the loss of vacuum to some extent by storing the tubes in precise temperature conditions. However, even if they are produced with better 10 more watertight materials and joints, and even if they are stored optimally, it cannot be avoided that the tubes lose their suction capacity over time and therefore have a limited shelf life, or whatever It is the same, an expiration.
     fifteen
    The purpose of the present invention is to provide a blood collection tube that is capable of presenting optimal vacuum conditions at the time of use, and at the same time presenting a reasonable cost so as to constitute a viable alternative to the tubes. Vacuum used today. twenty
    Brief Description of the Invention

    The present invention has as its object a device for collecting blood or a blood compound, which can be manipulated at the time of its use to create conditions of depression or emptiness inside, and that once created the vacuum can present a final shape analogous to a conventional tube so that it can be used in standard or conventional medical systems and equipment such as centrifugal machines, support racks and pipetting, etc. without requiring specific accessories to be used. The device has a very effective and at the same time simple configuration, which allows the construction of a disposable tube at a reasonable cost.

    The device according to the invention comprises a tube, a handle assembly, a piston assembly and a pierceable sealing element. The tube is
    it extends along a longitudinal axis and has a side wall, a closed distal end, a proximal end opposite the distal end and an inner cavity communicated with the outside by an opening in said proximal end. The piston assembly is movable along the inner cavity of the tube, in tight contact with the side wall of the tube, 5 and has at least one inner clipping surface and a longitudinal inner cavity. The piston assembly delimits a space between said piston assembly and the distal end of the tube. The handle assembly, in turn, has a gripping portion, a separable zone (for example breakable, detachable or with a detachable clipping) and an end portion 10 extending from said separable zone. The extreme portion has a longitudinal interior cavity and at least one clipping surface. The end portion of the handle assembly is movable with respect to the piston assembly to a position where at least one clipping surface of the end portion contacts an inner clipping surface of the piston assembly preventing removal of the end portion of the piston assembly . In said position, the pierceable sealing element prevents the passage of fluid from the delimited space between said piston assembly and the distal end of the tube and into the longitudinal interior cavity of the end portion of the handle assembly. In addition, in said position that the grip portion of the handle assembly is accessible from outside the device. The user can therefore, in said clipping position, push back the assembly formed by the handle assembly, the piston assembly and the pierceable sealing element to a position closer to the proximal end of the tube, creating a depression in the tube caused by the recoil of the piston assembly and the consequent increase in volume of the bounded space between the piston assembly and the distal end of the tube. Then, the user can separate and remove an important part of the handle assembly, obtaining a vacuum closed tube with a tight seal and pierceable by a needle. 30

    Because the container of the present invention allows the vacuum to be generated just before being used, it is possible to have optimum vacuum conditions at the time of using the container without therefore the container having to be manufactured with expensive materials or stored in strict temperature conditions. Manufacturing the
    Container of the present invention with usual materials, of reasonable cost, it has been found that optimum vacuum conditions can last for the time required by common applications in which blood taken from the human or animal body is used (for example 1, 2 or more hours). 5

    The device of the present invention is further advantageous in that it only has one open end provided with closure pieces (the proximal end of the tube), which allows greater centrifugal pressures when the centrifugal force acts against the distal and semi-spherical end of the tube, which has no continuity solution.
    Brief description of the figures

    The details of the invention can be seen in the accompanying figures, which are not intended to be limiting the scope of the invention:

    - Figure 1 shows a perspective view of an example of a blood collection device or a blood compound 20 according to the invention.
    - Figure 2 shows an exploded view of the device of Figure 1, showing the tube, the handle assembly, the pierceable sealing element, the piston assembly and the cover.
    - Figure 3 shows a sectional view of the end of the handle assembly of Figure 2 in which the end portion and the separable zone are located.
    - Figure 4 shows a sectional view of the pierceable sealing element of Figure 2.
    - Figure 5 shows a sectional view of the lid of Figure 2.
    - Figure 6 shows a sectional view of the piston assembly of Figure 2.
    - Figure 7 shows a sectional view of the device of Figure 1 in a first pre-assembly situation. 35
    - Figure 8 shows a sectional view of the device of the
    Figure 1 in a second situation, in which the handle assembly, the sealing element and the piston assembly have been introduced into the tube and the cover fixed to the tube.
    - Figure 9 shows a sectional view of the device of Figure 1 in a third situation, in which the handle assembly, piston assembly and perforable sealing element have been pushed to the bottom of the tube.
    - Figure 10 shows an enlarged view of the piston assembly, the pierceable sealing element and the end portion of the handle assembly in the situation of Figure 9. 10
    - Figure 11 shows a sectional view of the device of Figure 1 in a fourth situation, in which the handle assembly has been pushed, causing the handle assembly to be clipped to the piston assembly and that the pierceable sealing element remains in its final position ensuring sealing. fifteen
    - Figure 12 shows an enlarged view of the piston assembly, the pierceable sealing element and the end portion of the handle assembly in the situation of Figure 11.
    - Figure 13 shows a sectional view of the device of Figure 1 in a fifth situation, in which it has been pulled back 20 of the handle assembly, causing the recoil of the handle assembly, piston assembly and pierceable sealing element, generating a depression inside the tube
    - Figure 14 shows an enlarged view of the piston assembly, the pierceable sealing element, the end portion of the handle assembly 25 and the cover in the situation of Figure 13.
    - Figure 15 shows a sectional view of the device of Figure 1 in the fifth situation, where the section plane is perpendicular to the section plane of Figure 13.
    - Figure 16 shows an enlarged view of the piston assembly, the pierceable sealing element, the end portion of the handle assembly and the cover of Figure 15.
    - Figure 17 shows a sectional view of the device of Figure 1 in a sixth situation, in which the handle assembly has been pulled back and the handle assembly has been turned clockwise, causing the piston assembly to remain
    clipped to the lid.
    - Figure 18 shows an enlarged view of the piston assembly, the pierceable sealing element, the end portion of the handle assembly and the cover in the situation of Figure 17.
    - Figure 19 shows a sectional view of the device of Figure 5 in a seventh situation, in which the handle assembly in the separable zone has been broken, and the complete handle assembly removed except the end portion, leaving a container at Vacuum and pierceable for use to collect blood by suction effect, or for another application. 10
    - Figure 20 shows an enlarged view of the piston assembly, the pierceable sealing element, the end portion of the handle assembly and the cover in the situation of Figure 19.
    - Figure 21 shows a sectional view of a second embodiment of the device according to the invention in which the handle assembly has a detachable area clipped, said device having been represented in a situation analogous to the situation of Figure 17, is that is, in which the handle assembly has been pulled back and the handle assembly has been turned clockwise, causing the piston assembly 20 to be clipped to the lid.
    - Figure 22 shows an enlarged view of the piston assembly, the pierceable sealing element, the separable zone and end portion of the handle assembly, and the cover in the situation of Figure 21. 25
    - Figure 23 shows a sectional view of the device of Figure 21, in a later situation in which most of the handle assembly has been unclipped and removed, leaving a vacuum and perforable container for use to collect blood by effect suction, or for another application. 30
    - Figure 24 shows an enlarged view of the piston assembly, the pierceable sealing element, the separable zone and end portion of the handle assembly, and the cover in the situation of Figure 23.
    - Figure 25 shows an enlarged view of a third embodiment of the device according to the invention, in a situation
    in which the end portion of the handle assembly has not yet been clipped to the piston assembly.
    - Figure 26 shows the device of Figure 25, in a later situation in which the end portion of the handle assembly has been clipped to the piston assembly. 5
    - Figure 27 shows an enlarged view of a fourth embodiment of the device according to the invention, in a situation in which the end portion of the handle assembly has not yet been clipped to the piston assembly.
    - Figure 28 shows the device of Figure 27, in a subsequent situation in which the end portion of the handle assembly has been clipped to the piston assembly.
    - Figure 29 shows an enlarged view of a fifth embodiment of the device according to the invention, in a situation in which the handle assembly has not yet been clipped to the piston assembly.
    - Figure 30 shows the device of Figure 29, in a later situation in which the end portion of the handle assembly has been clipped to the piston assembly.
     twenty Detailed description of the invention

    The invention relates to a device for collecting blood or a blood compound as a result of suction or vacuum, and in particular a device having a tube, a piston assembly and a detachable handle assembly 25 to generate the vacuum in the tube moments before using the device, guaranteeing optimal vacuum conditions at the time the device is used for example to collect blood taken from a patient.
     30
    Figures 1 to 20 show an exemplary embodiment of said device. In particular, Figure 1 shows an external perspective of the device (1), in assembled state. Figure 2, in turn, shows an exploded perspective of the device (1), allowing to illustrate the different components thereof. 35

    In Figure 2 it can be seen that the device (1) of the present embodiment comprises a tube (10), a pulling assembly (30), a piston assembly (50), a pierceable sealing element (70) and a cover (90 ).

    The tube (10) extends along a longitudinal axis (11) and 5 has a side wall (12), a distal end (13), a proximal end (14) opposite the distal end (13) and a cavity interior (15), not visible in the present figure. Figure 7 shows the tube (10) in section, the inner cavity (15) being visible, which is communicated with the outside of the tube (10) through an opening (16) located in said proximal end 10 (14). The distal end (13) of the tube is a closed end. Preferably, the tube (10) is made entirely in one piece and material, for example of glass, or injected plastic, so that the walls of the distal end (13) are a continuation of the side wall (12). fifteen

    The handle assembly (30), as can be seen in Figure 2, has an elongated body (31) and a grip portion (32) or handle, which in the embodiment shown is at one end of the elongated body (31 ) and forms a T with the elongated body (31). The handle assembly (30) further comprises a separable zone (33) and an end portion (34) extending from said separable zone (33) and in the opposite direction to the grip portion (32) (i.e., in a end of the elongated body (31) opposite the end where the grip portion (32) is located. The end portion (34) has a longitudinal interior cavity 25 (35). Figure 3 shows an enlarged view of the end of the handle assembly (30), the arrangement of the separable zone (33) made in the form of a notch or narrowing between the elongated body (31) and the end portion (34) being more clearly seen. ). In the embodiment shown, the separable zone 30 (33) is breakable, that is, it is possible to separate the grip portion (32) of the handle assembly (30) from the end portion (34) of the handle assembly (30) by breaking said separable zone (33) of the handle assembly (30). The end portion (34) of the handle assembly (30) has at least one clipping surface (36), intended to be clipped to the piston assembly (50) as will be explained below, and at least one surface
    side (37) oblique and of increasing width towards the clipping surface (36), which contributes to causing the clipping. The lateral surface (37) can be conical, curved or a combination of both.

    The piston assembly (50), as can be seen in Figure 2 and 5 in greater detail in Figure 6, in turn has a main body (51) arranged around a longitudinal central axis (52). The main body (51) comprises a through cavity (53), also longitudinal; said inner cavity (53) is delimited by an inner wall (54). The main body (51) further comprises at least 10 an inner clipping surface (55) arranged radially or transversely. In the embodiment shown, the piston assembly comprises in particular two inner clipping surfaces (55). More specifically, the main body (51) comprises an annular outer surface (56), arranged around the inner cavity (53) and oriented towards the handle assembly (30), from which two elastic pins (57) extend. The elastic pins (57) are provided with a transversely flexible trunk (58) and a head (59), said trunk (58) and said head (59) forming an approximate shape of T. The head (59) has a part upper (60) oblique, which can be conical, curved or a combination of both, and which in the present embodiment is substantially hemispherical; in its lower zone, the head (59) has a transverse lower part on each side of the trunk (58), one of said transverse lower parts being the inner clipping surface (55) and the other of said transverse lower parts 25 being a outer clipping surface (61).

    As can be seen in Figure 8, a space (15a) is defined between the piston assembly (50) and the distal end (13) of the tube (10). The piston assembly (50) is movable along the inner cavity (15) of the tube (10) and in tight contact with the side wall (12) of the tube (10), so that when the piston assembly is sealed tightly (50) along the inner cavity (15) and towards the proximal end (14) there is a depression in the space (15a) delimited between the piston assembly (50) and the distal end (13) of the tube ( 10). To provide the tight contact, the piston assembly (50)
    of the present embodiment it comprises an elastic skirt (62), more clearly visible in Figure 6. Said skirt (62) extends backwards from a joining area (64) in an end portion of the main body (51), and it is elastic so that it can be folded laterally inwardly and outwardly with respect to said joint zone (64), which functions as a hinge. When the skirt (62) tends to open elastically in the radial direction, as will be seen later, it can thus be adjusted tightly against the side wall (12) of the tube (10).
     10
    The pierceable sealing element (70), visible in Figure 2 and in greater detail in Figure 4, has a disc-shaped head (71), and a trunk (72) narrower than the head (71) and extending from said head (71) in the longitudinal direction. An inner cavity (73) is disposed in the trunk (72), practically in its entire length; in 15 the embodiment shown, for example, the inner cavity (73) is arranged along more than three quarters of the length of the trunk (72).

    The cover (90), visible in Figure 2 and in greater detail in Figure 5, in turn consists of a transverse wall (91) and a side wall (92), between which an interior space (93) is delimited ). The side wall (92) has an inner surface (94) and an outer surface (95). The interior space (93) and the interior surface (94) are adapted in size and shape to receive the proximal end 25 (14) of the tube (10); for example, in the present embodiment, the inner surface (94) is cylindrical and has a diameter only slightly larger than the outer diameter of the tube (10) to allow a smooth but tight placement of the cap (90) on the tube (10) In the transverse wall (91) there is a hole (96) that is connected 30 with the interior space (93). Through the hole (96) and the interior space (93) the elongated body (31) of the handle assembly (30) is allowed, as explained in detail below. The hole (96) is generally cylindrical, and comprises at least one radial recess (97) that provides a transverse seat surface or surface of clipping (98). Said radial inlet (97) is communicated with the space
    inside (93) by a helical channel (99).

    Figures 7 to 20 show a sequence of use of the device (1) according to the invention, along which the different components of the device (1) are assembled and in which 5 vacuum conditions are created inside the device (one).

    Figure 7 illustrates a first step, in which the cover (90) is placed in the handle assembly (30) by inserting the end portion (34) and the elongated body (31) of the handle assembly (30) through the hole (96 ) and the inner space 10 (93) of the cover (90). The pierceable sealing element (70) is coupled to the end portion (34) of the handle assembly (30), specifically inserting the trunk (72) and part of the head (71) of the pierceable sealing element (70) into the longitudinal interior cavity (35) of said end portion (34). Next, the piston assembly (50) next to the end portion (34) and the pierceable sealing element (70) is arranged.

    Next, as shown in Figure 8, the end portion (34) of the handle assembly (30), the pierceable sealing element (70) and the piston assembly (50) are introduced into the inner cavity (15) of the 20 tube (10), through the opening (16), and the cover (90) is fixed to the tube (10). In the present embodiment, for example, the tube (10) has an outer thread (17), visible in Figures 2 and 7, to which a corresponding thread is screwed into the inner surface (94) of the wall side (92) of the cover (90) (said corresponding thread 25 not being shown in the figures). Once the cover (90) is fixed, the relatively tight size of the hole (96) of the cover with respect to the elongated body (31) of the pulling assembly (30) prevents the pulling assembly (30) from leaving the tube (10) . Then, by exerting a sufficient pushing force on the grip portion (32) of the handle assembly (30) in the direction of the tube (10) as indicated by the arrow (A), the assembly formed by the handle assembly is caused (30), the piston assembly (50) and the pierceable sealing element (70) overcome friction between the piston assembly (50) and the side wall (12) of the tube (10), and advance towards the bottom of the inner cavity (15) of the tube (10). As the piston assembly (50) advances 35 towards the distal end (13) of the tube (10), an increase in
    air pressure in space (15a) in front of the piston assembly (50). Said increase in pressure causes the pressure in front of the piston assembly (50) to be greater than behind the piston assembly (50), which results in a resulting force on the skirt (62) of the piston assembly (50) towards inside, as indicated schematically 5 with the arrow (B). Consequently, the skirt (62) folds slightly inwards with respect to the junction zone (64), and gaps are formed between the skirt (62) and the side wall (12) of the tube (10), allowing passage of air from space (15a) through said gaps and therefore the piston assembly (50) can move forward. 10

    If the force application is maintained, there comes a time that the situation of Figure 9 is reached, in which the piston assembly (50) reaches the bottom of the inner cavity (15) of the tube (10) and cannot advance further . Figure 10 shows an enlarged view of the 15 piston assembly (50) in this situation. As can be seen, until now the extreme portion (34) of the pulling assembly (30) has pushed the piston assembly (50) to the bottom of the tube (10) by a force exerted by the lateral surface (37) of the extreme portion (34) of the handle assembly (30) on the upper part (60) of the head (59) of the corresponding elastic pin (57) of the piston assembly (50), and by a force exerted by the pierceable sealing element (70 ) against the inner wall (54) of the piston assembly (50) equal to the frictional force between said pierceable sealing element (70) and said inner wall (54) of the piston assembly (50). 25

    If, from the situation of Figures 9 and 10, a sufficient pushing force is exerted on the grip portion (32) of the handle assembly (30) in the direction towards the tube (10), the situation of Figures 11 is reached and 12, in which the end portion (34) of the handle assembly 30 (30) is clipped to the piston assembly (50). More specifically, as can be seen more clearly by observing the sequence formed by Figures 10 and 12, if sufficient thrust force is exerted, the puller assembly (30) advances with respect to the piston assembly (50) - which cannot be displaced by having reached the bottom of the inner cavity (15) -, and the lateral surface (37) of the end portion (34)
    push the upper part (60) of the head (59) of the corresponding elastic pin (57). Because the lateral surface (37) and the upper part (60) are oblique, the longitudinal thrust of the lateral surface (37) causes the elastic pins (57) to open transversely, and the end portion (34) of the assembly shooter (30) 5 can overcome the head (59) of the elastic pins (57), reaching the situation of Figures 11 and 12, in which the clipping surface (36) of the end portion (34) contacts a corresponding inner clipping surface (55) of the piston assembly (50) preventing the extraction of the end portion (34) of the piston assembly (50). In this situation, in addition, 10 the pierceable sealing element (70) is disposed in a final position in which it prevents the passage of fluid through the inner cavity (53) of the piston assembly (50) and the longitudinal inner cavity (35 ) of the end portion (34) of the handle assembly (30), namely the head (71) and part of the trunk (72) of the piston assembly arranged 15 closing the fluid passage. Furthermore, in this situation, as can be seen in Figure 11, the grip portion (32) of the handle assembly (30) remains accessible from outside the device (1).

    From the clipping situation of Figures 11 and 12, the process of preparing the device (1) is continued by pulling the grip portion (32) of the handle assembly (30) backwards as indicated by the arrow (C), causing the handle assembly (30) to begin to retract along the inner cavity (15) of the tube (10) guided by the cover (90). Because the piston assembly (50) is clipped to the end portion (34) of the handle assembly (30), the piston assembly (50) and the pierceable sealing element (70) recede together with the handle assembly (30) . The recoil of the piston assembly (50) causes a depression in the part of the inner cavity (15) of the tube (10) that is between the piston assembly (50) and the distal end (13) of the tube (10). This depression causes the resulting force exerted against the skirt (62) by the air in front of and behind the piston assembly (50) to be outward as shown by the arrow (D), causing the skirt (62 ) is held down against the side wall (12) of the tube (10) and said contact causes a tight seal against the side wall (12) 35 that prevents the passage of air around the piston assembly (50).

    The recoil of the piston assembly (50) ends when the situation illustrated in Figures 13 and 14 is reached, in which the head (59) of the elastic pins (57) contacts the side wall (92) of the cover (90) ). At that time, each head (59) of each elastic pin (57) is located 5 at the entrance of a respective helical channel (99) of the cover (90). Figures 15 and 16 show two sectional views of the device (1) in the same situation of Figures 13 and 14, but the section having been made with a section plane that forms approximately 90 ° with the section plane corresponding to Figures 13 and 14. In Figures 15 10 and 16 it can be seen that the helical channel (99) flows into the radial recess (97) where the clipping surface (98) is located.

    From the situation of Figures 13 to 16, the user continues to pull the grip portion (32) of the handle assembly (30) while rotating said grip portion (32) - and therefore the handle assembly (30) complete - clockwise. Consequently, the heads (59) of the elastic pins (57) penetrate the corresponding helical channels (99) of the cover (90), and there is a slight further recoil of the assembly formed by the handle assembly (30), the 20 piston assembly (50) and the pierceable sealing element (70) at the same time as the rotation of said assembly with respect to the longitudinal axis (11) of the tube (10) as the heads (59) of the elastic pins (57 ) are ascending through respective helical channels (99). Because the space (15a) is under reduced pressure due to the recoil of the piston assembly (50), the pressure and tightness of the skirt (62) against the side wall (12) of the tube (10) is maintained.

    When the user has rotated the grip portion (32) approximately 90 ° clockwise, the piston assembly (50) reaches 30 a second rotational position illustrated in Figures 17 and 18. In this situation or second rotational position, the head (59 ) of each elastic pin (57) has reached a radial recess (97) of the cover (90) and in which the outer clipping surface (61) of each head (59) has come into contact and rests against the surface of clipping (98) of the corresponding radial inlet (97). Consequently, the extreme portion (34) of the
    handle assembly (30) is clipped to the piston assembly (50) so that it cannot retract outwards from the tube (10), and the piston assembly (50) in turn is clipped to the cover (90) so which cannot move into the tube (10). In the space (15a) between the piston assembly (50) and the distal end (13) of the tube (10), in turn, optimum depression conditions are ensured, guaranteed by the tight contact of the piston assembly (50) against the side wall (12) of the tube (10).

    Once this vacuum and clipping situation has been reached, the user breaks the handle assembly (30) through the separable zone (33), for example by pulling the grip portion (32) and / or rotating it again, and removes the elongated body (31) and the grip portion (32) of the handle assembly (30), reaching the situation of Figures 19 and 20. As can be seen, by means of the invention a final container or tube 15 has been obtained which, analogously to a conventional preloaded vacuum tube, has an interior space (15a) with reduced pressure or vacuum conditions, and is permanently closed at one end (the distal end (13)) while the other end (the proximal end (14)) It is closed by a perforable waterproof closure. Said perforable seal 20 is provided by the assembly formed by the cover (90), the piston assembly (50), the pierceable sealing element (70) and the end portion (34) - which remains clipped to the piston assembly (50) - . In this final situation, the piston assembly (50) cannot move forward or backward along the tube (10) because it is clipped to the cover (90). 25

    However, unlike a conventional pre-filled vacuum tube, the vacuum conditions of the tube of the invention at the time of use are optimal Thus, in the container of the present invention, the vacuum conditions are generated at the time 30 of its use, by means of the simple operation explained in the previous paragraphs. Once the handle assembly is separated, a tube similar to conventional tubes remains, which can be used to collect blood taken from a person or animal, introduced into a centrifuge machine, placed on a tube rack, etc. 35

    In the present embodiment, the handle assembly (30) is manufactured in one piece, for example entirely injected in plastic, and the separable zone (33) of the handle assembly (30) is a breakable zone, which simplifies manufacturing of the handle assembly (30). To facilitate said breakage, as can be seen in Figure 3, the separable zone 5 (33) of the handle assembly (30) may have a transverse dimension smaller than the end portion (34) of the handle assembly (30). For example, the separable zone (33) of the present embodiment is a notch or area of reduced diameter. Furthermore, in the present embodiment, the longitudinal interior cavity (35) of the end portion 10 (34) extends along the entire separable zone (33). This makes it possible to minimize the thickness of the walls of the separable zone (33) and ensure that the separable zone (33) is broken with relative ease.

    In addition, as can be seen for example in Figure 18, the perforable sealing element (70) of the present embodiment is disposed within the longitudinal interior cavity (35) of the end portion (34) of the handle assembly (30), and along the separable zone (33). This allows, although the walls of the separable zone (33) are thin, the effective thickness of the assembly formed by the handle assembly (30) and the pierceable sealing element (70) in the area of the separable zone (33) is Increase and therefore the separable zone (33) does not break when the steps prior to breaking the handle assembly (30) (steps of Figures 7 to 18) are being performed.
     25
    Figure 20 further illustrates that the presence of the inner cavity (73) of the pierceable sealing element (70) makes it possible to minimize the thickness or height (h) of the layer of sealing material in the longitudinal direction and in the central area of the pierceable sealing element (70), while ensuring that the total height of the perforable sealant element 30 (70) is held high to perform the reinforcing functions explained in the preceding paragraphs. This facilitates the insertion of a needle through said central area when the device is used to collect blood or another compound.
     35
    In the present embodiment, as can be seen in
    Figure 3, the clipping surface (36) of the distal end (13) of the handle assembly (30) is disposed perimetrically and continuously around a central longitudinal axis of the distal end (13). This allows the handle assembly (30) to be clipped to the piston assembly (50) in any relative rotational position between them. 5

    Preferably, as shown in Figure 6, the elastic skirt (62) of the piston assembly (50) has an increasing width; for example, in the embodiment shown, the skirt (62) is conical. This allows the skirt (62) to fit tightly against the side wall 10 (12) of the tube (10) regardless of whether the wall of the tube (10) is perfectly cylindrical or, on the contrary, has a slight taper or other slight variation so. Furthermore, in the present embodiment, the skirt (62) has a wavy outer contour (63), which favors the tight fitting of the skirt against the side wall 15 (12) of the tube (10). This undulating shape has a lower stiffness when sliding inside the tube when the inner wall (12) has a conical surface. In this way the material of the piston assembly itself (50) looks less requested and can be less sophisticated.
     twenty
    Figures 21 to 24 show a second embodiment of a device (100) according to the invention, generally equal to the previous embodiment, including the fact that the device (100) comprises a pulling assembly (130) that includes a body elongate (131), a grip portion (132), a separable zone (133) and an end portion (134), where the latter has a longitudinal interior cavity (135) and at least one clipping surface (136). However, as can be seen in Figures 21 and 22, the device (100) according to the invention differs from the embodiment of Figures 1 to 20 in that the grip portion (132) and the end portion (134) of the Puller assembly (130) are two separate pieces, and in which the separable zone (133) is a clipping or clipping disconnectable joint present between the grip portion (132) and the end portion (134).

    Figures 21 and 22 show the device (100) in a situation 35 analogous to the situation of Figure 17, that is, in which it has been pulled
    towards the rear of the handle assembly (130) and the handle assembly (130) has been turned clockwise, causing the piston assembly (50) to be clipped to the cover (90) in the same way as in the previous embodiment. Then, if the user exerts a sufficient tensile force on the grip portion (132) of the handle assembly (130), the situation of Figures 23 and 24 is reached, in which the clipated junction of the area is plucked separable (133) and the grip portion (132) of the end portion (134) of the handle assembly (134) has been separated. Again, a container has been obtained that has a vacuum space (15a) delimited by a tube (12) closed by a lid (90) and a piston assembly (50) clipped to the lid (90), and said being space (15a) separated from the outside by a perforable element (70). Under these conditions, the tube can be used to draw blood, centrifuge blood, or other applications. To access said space (15a), it is possible to insert a needle through the longitudinal inner cavity 15 (135) of the end portion (134), the pierceable element (70) and the inner cavity (53) of the piston assembly ( 50), getting communication for the passage of a fluid through it.

    Figures 25 and 26 show a third embodiment of a device (200) according to the invention. The device (200) of the present embodiment has, like the previous embodiments, a tube (10), a cover (90) –not shown-, a piston assembly (250) provided with an inner cavity (253) of fluid passage, a pierceable sealing element (270) for sealing a space (15a) in the tube (10) , and a handle assembly (30) accessible from the outside to move the piston assembly (250). Furthermore, like the device (100) of the first embodiment, the handle assembly (30) of the present embodiment is constructed in one piece and with a separable zone (33) breakable; The end portion (34) of the handle assembly (30) also has a longitudinal interior cavity (35).

    However, the present device (200) differs from the previous embodiments in that the pierceable sealing element (270) forms part of the piston assembly (250), that is, at all times it travels
    with the piston assembly (250). In addition, the piston assembly (250) comprises an inner element (250a), which comprises the inner cavity (253) of the piston assembly (250). In the present embodiment, the pierceable sealing element (270) is exterior, and comprises a transverse outer cover (270a) and an outer wall (270b) extending 5 from the outer cover (270a) and surrounding a portion of the inner element (250a). The outer cover (270a) has a through hole (270c) aligned with the inner cavity (253). As shown in Figure 25, when the piston assembly (250) travels towards the distal end (13) of the tube (10) without the handle assembly 10 (30) has yet been clipped to the piston assembly (250), the space air (15a) is dislodged through the through hole (270c) and the inner cavity (253), allowing the piston assembly (250) to advance towards the bottom of the tube (10). As shown in Figure 26, once the piston assembly (250) has reached the bottom of the tube (10) and the handle assembly (30) has been clipped to the piston assembly (250), the end portion (34 ) of the handle assembly (30) is partially inserted into the inner cavity (253), sealing it tightly and preventing the evacuation of air from the space (15a) through the through hole (270c) and the inner cavity (253). Then, if from the clipping situation of Figure 26, the handle assembly 20 is pulled (30) and the piston assembly (250) is retracted, a depression is formed in the space (15a).

    In certain embodiments, the inner element (250a) can be rigid to provide robustness to the piston assembly (250), while the elastic outer perforable sealing element (270) guarantees the tight contact against the wall (12) of the tube (10)

    In alternative embodiments, the inner element (250a) may be slightly smaller than the end portion (34) 30 of the handle assembly (30), so that when the end portion (34) is clipped to the interior element (250a) it causes an elastic widening of the latter, which in turn pushes out the pierceable sealing element (270), increasing the tight contact against the wall (12) of the tube (10). This ensures that the contact between the piston assembly (250) and the tube wall (10) is less when it is
    pushing the handle assembly (30) into the tube (10), and that the contact is greater when the clipping between the handle assembly (30) and the piston assembly (250) has already occurred and the handle assembly is pulled ( 30) in the reverse direction, to create the vacuum. This effect can facilitate the use of the device, since in the pushing direction 5 of the handle assembly (30) into the tube (10) it is possible to exert a lower force.

    Figures 27 and 28 show a variant of the previous embodiment, in situations analogous to those of Figures 25 and 26. In the present embodiment of Figures 27 and 28, the outer cover (270a) has no hole . In addition, at least the portion of the inner element (250a) of the piston assembly (250) that is surrounded by the outer wall (270b) of the pierceable sealing element (270) applies an elastic thrust against the outer wall (270b) of the sealing element 15 (270). Specifically, in the present embodiment, said elastic thrust is exerted by elastic side pins (290), which are inserted into the deformable perforable sealing element (270), so that they tend elastically to open (push radially towards outside) and therefore to widen the pierceable sealing element (270) and thereby contribute to the tight contact between the outer wall (270b) of the sealing element (270) and the side wall (12) of the tube (10). That is, the elastic side pins (290) and the outer wall (270b) have a joint operation analogous to the collapsible elastic skirt (62) of the first embodiment of Figures 1 25 to 24.

    Figures 29 and 30 show an embodiment of a device (300) alternative to the previous ones. The present device (300) comprises a handle assembly (330) and a piston assembly 8350) movable within a tube (10). The handle assembly (330) is provided with an elongated body (331), a grip or handle portion - not shown - and a threaded end portion (334), that is, provided with an external threaded profile (334a). The end portion (334) has a longitudinal interior cavity (335), at least a surface of 35 clipping (336), intended to be clipated to the piston assembly (350), and at least
    an oblique side surface (337) and of increasing width towards the clipping surface (336), which contributes to causing the clipping, similarly to previous embodiments. The clipping surface (336) and the lateral surface (337) of the present embodiment form part of the external threaded profile (334a). The piston assembly (350), in turn, is formed by a first piece (351) provided with elastic pins (357) similar to those of previous embodiments; said elastic pins (357) comprise an inner clipping surface (355) and an outer clipping surface (361), intended to be clipated respectively with a clipping surface (336) and with the cap -not 10 represented-, similarly to previous embodiments. The piston assembly (350) of the present embodiment has a skirt (362) of operation analogous to that of the skirt (62) of the first embodiment described herein.
     fifteen
    The thrust and clipping of the present embodiment occurs differently than the previous embodiments. On the one hand, as Figure 29 illustrates, the piston assembly (350) can be pushed along the tube (10) by the handle assembly (330) until it reaches the bottom of the tube (10). Then, if you continue pushing the handle assembly 20 (330) with sufficient force, the conical lateral surfaces (337) push and deform the elastic pins (357) and it is produced that the end portion (334) is inserted between the elastic pins ( 357), said end portion being clipped (334) by means of the contact and top between the clipping surfaces (336) and the inner clipping surfaces 25 (355) of the elastic pins (357).

    The disconnection of the handle assembly (300) from the piston assembly (350) occurs differently. Once the puller assembly (330) and the piston assembly (350) are retracted until they are clipped to the plug (in a manner analogous to Figure 18), the puller assembly (330) is unscrewed from the elastic pins (357) making turn the handle assembly (330) with respect to the piston assembly (350), which is rotationally fixed in said direction of rotation because it abuts the stopper.
     35
    The present embodiment comprises a sealing element
    perforable (370) that is part of the piston assembly (350). The rest of the piston assembly (350) can be made of one or more pieces (the example illustrated includes two) and one more materials of varying stiffness.

    Alternative embodiments are contemplated in which the threaded handle assembly configuration (300) described with reference to Figures 29 and 30 is used in combination with any other type of piston assembly (350) within the scope of the claims.

    Alternative embodiments are contemplated in which the exact geometry of the parts that provide the claimed clipping surfaces may vary.

    Alternative embodiments are also contemplated in which partial voids can be made, for which the handle assembly 15 may have more than one separable zone.

    Various marketing or presentation formats of the device are also contemplated. For example, the device may be presented completely or partially disassembled. Alternatively, the device can be presented in situations analogous to that of Figure 11 (which coincides with Figure 1), that is, with the puller assembly and the piston assembly inserted to the bottom of the tube and the clipping having occurred between them, so that the user who is going to use the tube only has to unpack it, pull the handle assembly 25 backwards, turn the handle assembly and separate (eg break or unclip) it to obtain a tube with an optimum vacuum ready to be used

    The tube of the present embodiment may be made of glass, plastic or any other applicable material, and may or may not be provided with a surface treatment.
    权利要求:
    Claims (21)
    [1]

    1. Device (1; 100; 200; 300) for collecting blood or a blood compound, characterized in that it comprises:
     5
    - a tube (10) extending along a longitudinal axis (11) and having a lateral wall (12), a distal end (13), a proximal end (14) opposite the distal end (13) and an inner cavity (15) communicated with the outside by an opening (16) at said proximal end 10 (14);
    - a piston assembly (50; 250; 350) movable along the inner cavity (15) of the tube (10), said piston assembly (50; 250; 350) delimiting a space (15a) between the piston assembly (50 ; 250; 350) and the distal end (13) of the tube (10); fifteen
    - a handle assembly (30; 130; 330), which has a grip portion (32; 132) and an end portion (34; 134; 334), and
    - a pierceable sealing element (70; 270; 370); where
    - the device (1; 100; 200; 300) is adapted to adopt a forward position in which the handle assembly (30; 130; 230) 20 pushes the piston assembly (50; 150; 250) towards the distal end ( 13) and is not clipped to the piston assembly (50; 150; 250), and in which air housed in the space (15a) is dislodged through the piston assembly (50; 150; 250) and / or through a space between the piston assembly (50; 150; 250) and the side wall (12) of the tube (10); and where
    - the device (1; 100; 200; 300) is adapted to adopt a recoil position in which the end portion (34; 134; 334) of the handle assembly (30; 130; 230) is clipped to the piston assembly ( 50; 150; 250) and pulls the piston assembly (50; 150; 30 250) towards the proximal end (14), and in which the piston assembly (50; 150; 250) and the pierceable sealing element (70; 270 ; 370) tightly seal the space (15a).

    [2]
    2. Device (1; 100; 300) according to claim 1, characterized in that the piston assembly (50; 350) has a body
    main (51; 351) from which a skirt (62; 362) extends backwards, where said skirt (62; 362) is elastic and flexible and has an increasing width.

    [3]
    3. Device (1; 100; 300) according to claim
    2 , which is characterized in that the skirt (62; 362) has a wavy outer contour.

    [4]
    Device (1; 100; 200; 300) according to claim 1, characterized in that the piston assembly (50; 250; 350) comprises at least 10 an inner clipping surface (55; 255; 355), and because the end portion (34; 134; 334) has at least one clipping surface (36; 136; 336), where in said recoil position the inner clipping surface (55; 255; 355) of the piston assembly (50 ; 250; 350) engages with the clipping surface (336; 136; 336) of the end portion (34; 134; 15 334).

    [5]
    5. Device (1; 100; 200) according to claim
    4 , characterized in that the clipping surface (36; 136) of the handle assembly (30; 130) is arranged perimetrically and continuously about 20 a longitudinal axis of the handle assembly (30; 130).

    [6]
    Device (1; 100; 200; 300) according to claim 1, characterized in that the piston assembly (50; 250; 350) further comprises at least one outer clipping surface (61; 261; 361), and because the device (1; 100; 200; 300) further comprises a cover (90) that is fixed to the proximal end (14) of the tube (10) and which has a hole (96) through which the handle assembly ( 30; 130; 330) protrudes from the tube (10), wherein said cap (90) comprises at least one clipping surface (98) against which an outer clipping surface (61; 261; 361) 30 of the piston assembly can contact (50; 250; 350) when the handle assembly (30; 130; 330) and the piston assembly (50; 250; 350) are in an extended position with respect to the tube (10), preventing the advance of the piston assembly ( 50; 250; 350) and the handle assembly (30; 130; 330) towards a more compressed position with respect to the tube (10). 35

    [7]
    7. Device (1; 100; 200; 300) according to claim
    6 , characterized in that the piston assembly (50; 250; 350) is rotatable with respect to the tube (10) and the cover (90), and can adopt a first rotational position in which there is no contact between the surface of outer clipping (61; 261; 361) of the piston assembly (50; 250; 5 350) and a clipping surface (98) of the cover (90) and in which the piston assembly (50; 250; 350) with respect to the cover (90), and a second rotational position in which a contact occurs between the outer clipping surface (61; 261; 361) of the piston assembly (50; 250; 350) and a surface of clipping (98) of the 10 cover (90) and a longitudinal advance of the piston assembly (50; 250; 350) into the tube (10) is prevented.

    [8]
    8. Device (1; 100; 200) according to claim
    7 , characterized in that the piston assembly (50; 250) moves longitudinally 15 to move from the first rotational position to the second rotational position.

    [9]
    9. Device (1; 100; 200; 300) according to claim
    6 , characterized in that the piston assembly (50; 250; 350) has a main body 20 (51; 251; 351) from which one or more elastic pins (57; 257; 357) extend longitudinally, said pins being elastics (57; 257; 357) provided with a transversely flexible trunk (58; 258; 358) and a head (59; 259; 359), said trunk (58; 258; 358) and said head (59; 259) forming ; 359) a T-shape with an oblique upper part (60; 25 260; 360) and with a transverse bottom part on each side of the trunk (58; 258; 358) in a radial direction, said transverse bottom portions providing the surface outer clipping (61; 261; 361) and inner clipping surface (55; 255; 355).
     30
    [10]
    Device (1; 100) according to claim 1, characterized in that the pierceable sealing element (70) is disposed within a longitudinal interior cavity (35; 135) provided in the end portion (34; 134) of the assembly shooter (30; 130) and in said separable zone (33).
     35
    [11]
    11. Device (1; 100, 200) according to claim 1, which is
    characterized in that the handle assembly (30; 130) has a separable zone (33; 133), where the end portion (34; 134) extends from said separable zone (33; 133), and where the end portion (34, 134) can be separated from the rest of said handle assembly (30; 130) in said separable zone (33; 133). 5

    [12]
    12. Device (1; 200) according to claim
    eleven , characterized in that the separable zone (33) is breakable.

    [13]
    13. Device (1; 200) according to claim
    12 , characterized in that the separable area (33) of the handle assembly (30) has a transverse dimension smaller than the end portion (34) of the handle assembly (30), and that the longitudinal interior cavity (35) of the Extreme portion extends along the separable zone (33).
     fifteen
    [14]
    14. Device (100) according to claim 1, characterized in that the separable zone (133) comprises a disconnectable clipping.

    [15]
    15. Device (200) according to claim 1, characterized in that the pierceable sealing element (270) is comprised in the piston assembly (250), and in that the piston assembly (250) further comprises an inner element (250a ), where the pierceable sealing element (270) comprises a transverse outer cover (270a).

    [16]
    16. Device (200) according to claim
    fifteen , characterized in that the transverse outer cap (270a) blocks the passage of fluid between the space (15a) and the inner cavity (253).

    [17]
    17. Device (200) according to claim
    fifteen , characterized in that the transverse outer cover (270a) comprises a through hole 30 (270c) communicated with an inner cavity (253) of the piston assembly (250), where in said forward position the through hole (270c) and the Inner cavity (253) provide an air passage space through the piston assembly (250), and where in said recoil position, the end portion (34) blocks the flow of fluid through the piston assembly (250).

    [18]
    18. Device (200) according to claim
    fifteen , characterized in that the pierceable sealing element (270) further comprises an outer wall (270b) extending from the outer cover (270a) and surrounding a portion of the inner element (250a), the inner element being arranged between 5 (250a) and the side wall (12) of the tube (10) and in tight contact with said side wall (12) when the device (200) is in the reverse position.

    [19]
    19. Device (200) according to claim
    18 , characterized in that the pierceable sealing element (270) is elastic, and that at least the portion of the inner element (250a) that is surrounded by the outer wall (270b) of the perforable sealing element (270) applies a thrust elastic against the outer wall (270b) of the sealing element (270) contributing to the tight contact between the outer wall (270b) of the sealing element (270) and the side wall (12) of the tube (10) when the device (200) It is in the reverse position.

    [20]
    20. Device (200) according to claim
    18 , characterized in that the end portion (34) of the handle assembly (30) has a transverse dimension 20 greater than the interior cavity (253) of the interior element (250a), and that in said clipping position the end portion ( 34) is at least partially housed in said inner cavity (253) and radially pushes the inner element (250a) outwardly. 25

    [21]
    21. Device (300) according to claim 1, characterized in that the end portion (334) has an external threaded profile (334a), configured to clip the piston assembly (250) in said recoil position, and to, From a clipping situation, unscrew the piston assembly (250).
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    EP3305195B1|2019-07-10|
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    法律状态:
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    优先权:
    申请号 | 申请日 | 专利标题
    ES201530776A|ES2593042B1|2015-06-03|2015-06-03|Device for collecting blood or a blood compound|ES201530776A| ES2593042B1|2015-06-03|2015-06-03|Device for collecting blood or a blood compound|
    ES16726353T| ES2751678T3|2015-06-03|2016-05-23|Blood collection device|
    EP16726353.2A| EP3305195B1|2015-06-03|2016-05-23|Blood collection device|
    PT16726353T| PT3305195T|2015-06-03|2016-05-23|Blood collection device|
    BR112017025837-4A| BR112017025837B1|2015-06-03|2016-05-23|DEVICE FOR THE COLLECTION OF BLOOD OR BLOOD COMPOUND|
    KR1020177034501A| KR20180014711A|2015-06-03|2016-05-23|Blood collection device|
    CA2988027A| CA2988027C|2015-06-03|2016-05-23|Device for the collecting of blood or a blood compound|
    JP2017562709A| JP6737817B2|2015-06-03|2016-05-23|Equipment for blood collection|
    RU2017141930A| RU2694468C2|2015-06-03|2016-05-23|Device for taking blood or blood preparation|
    PCT/ES2016/070388| WO2016193513A1|2015-06-03|2016-05-23|Blood collection device|
    MX2017013467A| MX361558B|2015-06-03|2016-05-23|Blood collection device.|
    PE2017002500A| PE20171771A1|2015-06-03|2016-05-23|DEVICE FOR COLLECTION OF BLOOD OR A BLOOD COMPOUND|
    PL16726353T| PL3305195T3|2015-06-03|2016-05-23|Blood collection device|
    CN201680031851.XA| CN107735028B|2015-06-03|2016-05-23|Device for collecting blood or blood complexes|
    TW105117188A| TWI700108B|2015-06-03|2016-06-01|Device for the collecting of blood or a blood compound|
    US15/171,318| US10376194B2|2015-06-03|2016-06-02|Device for the collecting of blood or a blood compound|
    ARP160101640A| AR104885A1|2015-06-03|2016-06-02|BLOOD COLLECTION OR BLOOD COMPOUND DEVICE|
    CL2017002975A| CL2017002975A1|2015-06-03|2017-11-23|Device for collecting blood or a blood compound|
    CONC2017/0013373A| CO2017013373A2|2015-06-03|2017-12-26|Blood collection device|
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